Chlorothiazide
Keeb kwm
Chlorothiazide yog ib qho inhibitor ntawm carbonic anhydrase thiab muaj zog me ntsis dua li acetazolamide. Qhov kev sib xyaw no tau pom tias thaiv cov reabsorption ntawm sodium thiab chloride ions.
Kev piav qhia
Chlorothiazide yog diuretic thiab antihypertensive. (IC50 = 3.8 mM) Lub Hom Phiaj: Lwm Cov Chlorothiazide sodium (Diuril) yog ib qho tshuaj diuretic siv nyob rau hauv tsev kho mob los yog siv tus kheej los tswj cov kua dej ntau dhau uas cuam tshuam nrog lub plawv tsis ua haujlwm. Nws kuj tseem siv los ua cov tshuaj tiv thaiv hypertensive. Feem ntau feem ntau noj hauv daim ntawv tshuaj, nws feem ntau yog noj ib zaug lossis ob zaug hauv ib hnub. Hauv qhov chaw ICU, chlorothiazide tau muab rau cov neeg mob diurese ntxiv rau furosemide (Lasix). Ua hauj lwm nyob rau hauv ib tug nyias muaj nyias ib mechanism tshaj furosemide, thiab absorbed enterically raws li ib tug reconstituted ncua kev kawm ntawv los ntawm ib tug nasogastric raj (NG raj), ob cov tshuaj potentiate ib leeg.
Kev sim tshuaj
| NCT Num | Txhawb nqa | Qhov xwm txheej | Pib Hnub | Theem |
| NCT03574857 | University of Virginia | Lub plawv tsis ua hauj lwm | Lub plawv tsis ua hauj lwm nrog txo ejection feem | Lub plawv tsis ua hauj lwm mob | Cov kab mob plawv | Lub Rau Hli 2018 | Theem 4 |
| NCT02546583 | Yale University|National Heart, Lung, and Blood Institute (NHLBI) | Lub plawv tsis ua hauj lwm | Lub yim hli ntuj 2015 | Tsis siv tau |
| NCT02606253 | Vanderbilt University | Vanderbilt University Medical Center | Lub plawv tsis ua hauj lwm | Lub Ob Hlis 2016 | Theem 4 |
| NCT00004360 | National Center for Research Resources (NCRR)|Northwestern University|Office of Rare Diseases (ORD) | Ntshav Qab Zib Insipidus, Nephrogenic | Cuaj hlis 1995 |
|
| NCT00000484 | National Heart, Lung, and Blood Institute (NHLBI) | Kab Mob plawv | Kab Mob plawv | Mob ntshav siab | Vascular Disease | Plaub Hlis Ntuj 1966 | Theem 3 |
Cov qauv tshuaj
Tswv yim18Quality Consistency Evaluation tej yaam num uas tau pom zoo4, thiab6tej yaam num raug tso cai.
Advanced thoob ntiaj teb kev tswj hwm qhov system tau tso lub hauv paus ruaj khov rau kev muag khoom.
Kev saib xyuas zoo khiav los ntawm tag nrho lub neej voj voog ntawm cov khoom kom ntseeg tau tias qhov zoo thiab kho cov nyhuv.
Pab Pawg Kev Tswj Xyuas Kev Tswj Xyuas Kev Ua Haujlwm txhawb nqa qhov kev xav tau zoo thaum lub sijhawm thov thiab sau npe.
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