Crisaborole yog ib tug tswv cuab ntawm chav kawm ntawm benzoxaboroles uas yog 5-hydroxy-1,3-dihydro-2,1-benzoxaborole uas phenolichydrogentau hloov los ntawm 4-cyanophenyl pawg. Ib tug phosphodiesterase 4 inhibitor uas yog siv rau kev kho mob ntawm me me mus rau nruab nrab atopic dermatitis nyob rau hauv cov me nyuam thiab cov neeg laus. Nws muaj lub luag haujlwm ua phosphodiesterase IV inhibitor, ibtshuaj antipsoriaticthiab cov tshuaj uas tsis yog-steroidal anti-inflammatory. Nws yog benzoxaborole, uas muaj ntxhiab ether thiab nitrile.

Crisaborole yog ib qho tshiabtshuaj oxaboroleKev pom zoo los ntawm FDA thaum Lub Kaum Ob Hlis 14, 2016 raws li Eucrisa, ib qho tshuaj kho mob rau cov mob me me mus rau nruab nrab atopic dermatitis. Qhov no tsis yog-steroidal tus neeg sawv cev muaj txiaj ntsig zoo hauv kev txhim kho cov kab mob hnyav, txo qhov kev pheej hmoo ntawm kev kis kab mob thiab txo cov tsos mob thiab cov tsos mob ntawm cov neeg mob hnub nyoog 2 xyoos thiab laus dua. Nws txo qhov mob hauv zos hauv daim tawv nqaij thiab tiv thaiv kev kis tus kab mob ntxiv nrog kev nyab xeeb zoo. Nws cov qauv muaj aboronatom, uas pab txhawb kev nkag mus ntawm daim tawv nqaij thiab khi rau bimetal chaw ntawm phosphodiesterase 4 enzyme. Nws yog tam sim no nyob rau hauv kev loj hlob raws li kev kho mob ntawm psoriasis.

Crisaborole yog Phosphodiesterase 4 Inhibitor. Lub mechanism ntawm kev txiav txim ntawm crisaborole yog raws li Phosphodiesterase 4 Inhibitor.