Nyob rau hauv xyoo tas los no, kev muag khoom ntawmapixabantau loj hlob sai, thiab kev lag luam thoob ntiaj teb tau dhau los lawmrivaroxaban ua.Vim Eliquis (apixaban) muaj qhov zoo dua ntawm warfarin hauv kev tiv thaiv mob stroke thiab los ntshav, thiab Xarelto (Rivaroxaban) tsuas yog pom tias tsis muaj qhov tsis zoo.Ntxiv rau,Apixabantsis xav tau kev hloov kho cov tshuaj nyuaj, thiab cov tshuaj tau yooj yim dua.Qhov no series ntawm qhov tsis zoo tshwm simrivaroxaban uakom poob hauv av hauv Asmeskas kev lag luam.

Txawm li cas los xij, hauv Suav teb av loj,rivaroxaban uamuaj ntau qhov taw qhia thoob ntiaj teb thiab hauv Suav teb av loj.Lub sijhawm patent tas sij hawm ntawmrivaroxaban uayog nyob ze, thiab muaj cov tshuaj yuav ua rau cov pejxeem ntawmrivaroxaban uageneric tshuaj kom ho tshaj qhov uasApixaban.

Raws li Xianda cov ntaub ntawv, kev muag khoom hauv tsev ntawm rivaroxaban hauv 2018 yog 2.8 billion yuan.Raws li kev tshaj tawm ntawm Huahai Pharmaceutical, lub tsev kho mob hauv tsev muag khoom ntawmrivaroxaban uaHauv 2018 yog 1.527 billion yuan.

Ntawm chav kawm, cov npe ntawm cov tshuaj generic yuav ua rau muaj kev poob qis hauv ib hnub ntawm tus nqirivaroxaban ua.Muab rau hauv tus account tias ntawm tag nrho NOACs, patents raurivaroxaban uacov tebchaw yuav tag rau xyoo 2020 thaum ntxov (patents rauapixabanthiab dabigatran etexilate ntev dua Rau ib lub sij hawm ntev), nws yuav undoubtedly muaj txiaj ntsig rau kev txhawb nqa tag nrho.rivaroxaban uageneric tshuaj los hloov warfarin.Yog tus nqi txhua hnub ntawmrivaroxaban uageneric tshuaj yog launched los ntawm 27.6 yuan mus rau 2.76 yuan, qhov no kuj yuav ntxiv dag zog.

Tus naj npawb ntawm cov ntawv thov uas tsuas yog xav txog cov neeg mob atrial fibrillation (AF) kuj zoo kawg nkaus.Tus naj npawb ntawm cov neeg mob atrial fibrillation nyob rau hauv Suav teb yog kwv yees li 10 lab, ntawm uas muaj li 2 lab yog rau valvular atrial fibrillation thiab txog 7 lab rau non-valvular atrial fibrillation.Kev soj ntsuam hauv xyoo 2016 Nws tau pom tias qhov kev paub txog ntawm atrial fibrillation hauv Suav teb Mainland yog 40%, thiab tus nqi anticoagulation yog 30%.Rivaroxaban yooj yim siv, tsis tas yuav tsum tau saib xyuas cov ntsuas coagulation, thiab tus nqi ntawm cov tshuaj tiv thaiv coagulation kuj tseem yuav txhim kho zoo heev.Nws yog kwv yees hais tias cov tshuaj generic ntawmrivaroxaban uayuav nyob rau hauv Tuam Tshoj Mainland.Kev lag luam loj siv rau cov neeg mob uas tsis yog-valvular atrial fibrillation thiab atrial fibrillation: 7 lab cov neeg mob * 30% anticoagulation tus nqi * 50% nkag tus nqi * 2.76 yuan / hnub * 365 hnub = 157 lab yuan.

Tsis tas li ntawd, kev lag luam kev cia siab rau kev tiv thaiv thiab kho cov neeg mob VTE yog underestimated.Raws li kev txheeb cais ntawm VTE Lub Chaw Tiv Thaiv thiab Kho Mob hauv Tebchaws Meskas, tus naj npawb ntawm cov neeg mob VTE hauv Tebchaws Meskas muaj txog 900,000 txhua xyoo, thiab cov neeg tuag ntawm VTE nce mus txog 60,000 txog 100,000, thiab muaj Cov teeb meem mus sij hawm ntev (xws li DVT) cov neeg mob suav txog 50%, thiab tus naj npawb ntawm rov qab nyob rau hauv 10 xyoo suav txog 33%.

Vim yog cov neeg laus ntawm Tuam Tshoj, thiab cov pejxeem hauv paus yog ntau dua 4 npaug ntawm Tebchaws Meskas (1.395 billion tus neeg).Nws tuaj yeem kwv yees tias muaj 3.6 lab tus neeg mob VTE hauv Suav teb txhua xyoo.Piv txwv tias qhov kev kho mob 3 lub hlis ntawmrivaroxaban uayog 80%, kev lag luam loj yog: 3.6 lab tus neeg mob * 80% kev kho mob tus nqi * 2.76 yuan / hnub * 92 hnub = 731 lab yuan.

Yog li ntawd, tsuas yog xam ob qho kev qhia ntawm AF thiab VTE, kev lag luam hauv tsev loj ntawm rivaroxaban generic tshuaj yog ze rau 2 billion yuan.Nws yog txaus ua rau cov tuam txhab kws tshuaj hauv tebchaws maj nrawm mus thov rau npe.

Peb,Changzhou Pharmaceutical Factory, kuj tsimapxiabanthiabkev rivaroxban, thiab ob leeg muaj DMF.Rivaroxabantab tom ua tiav ntawm kev thov CEP thiab WC.