Ruxolitinibyog hom tshuaj kho mob qog noj ntshav. Nws yog tsuas yog siv los tiv thaiv kev ua haujlwm ntawm JAK-STAT signaling txoj hauv kev thiab txo cov teeb liab uas cuam tshuam qhov txawv txav, yog li ua tiav cov txiaj ntsig kho. Nws ua haujlwm los ntawm thaiv koj lub cev los ntawm kev tsim cov tshuaj hu ua kev loj hlob yam. Nws tsis tuaj yeem kho tau ib tus kab mob hauv thaj tsam ntawm hematology kho mob, tab sis kuj kho cov kab mob myeloproliferative neoplasms classical (tseem hu ua BCR-ABL1-negative MPNs), JAK exon 12 kev hloov pauv, CALR, thiab APL, thiab lwm yam.
Dab tsi yog qhov pom zoo pib koob tshuaj?
Nws tuaj yeem ua rau muaj kev phiv xws li myelosuppression ib yam nkaus, ua rau tsis tshua muaj, tab sis muaj peev xwm tshwm sim hauv chaw kho mob loj xws li neutropenia, thrombocytopenia, leukemia thiab anemia. Yog li yuav tsum tau saib xyuas tshwj xeeb hauv kev txiav txim siab pib koob tshuaj thaum muab tshuaj rau cov neeg mob. Qhov pom zoo pib koob tshuaj Ruxolitinib feem ntau yog nyob ntawm tus neeg mob PLT suav. Rau cov neeg mob uas platelet suav ntau dua 200, qhov pib koob tshuaj yog 20 mg ob zaug ib hnub; rau cov neeg uas muaj platelet suav nyob rau hauv thaj tsam ntawm 100 txog 200, qhov pib koob tshuaj yog 15 mg ob zaug ib hnub; Rau cov neeg mob uas muaj platelet suav ntawm 50 thiab 100, qhov siab tshaj plaws pib koob tshuaj yog 5 mg ob zaug ib hnub.
Kev ceev faj ua ntej nojRuxolitinib
Ua ntej, xaiv tus kws kho mob nrog kev paub nplua nuj hauv kev kho mob nrog Ruxolitinib. Qhia rau koj tus kws kho mob yog tias koj tsis haum rau nws, lossis yog tias koj muaj lwm yam kev ua xua. Nws yuav muaj cov khoom xyaw uas tsis muaj zog, uas tuaj yeem ua rau muaj kev tsis haum tshuaj lossis lwm yam teeb meem.
Qhov thib ob, tsis tu ncua sim koj cov PLT suav. Ua kom tiav cov ntshav suav thiab suav platelet yuav tsum tau sau tseg txhua 2-4 lub lis piam txij li thaum noj Ruxolitinib kom txog rau thaum cov koob tshuaj tau ruaj khov, thiab tom qab ntawd raug kuaj xyuas yog tias qhov ntsuas xav tau.
Thib peb, kho cov koob tshuaj kom zoo. Qhov koob tshuaj pib tsis tshua hloov yog tias koj noj Ruxolitinib tab sis muaj platelet tsawg thaum pib. Thaum koj cov PLT suav tau nce raws li qhov kev npaj kho mob sib koom ua ke, koj tuaj yeem maj mam nce koj cov koob tshuaj los ntawm kev ua raws li koj tus kws kho mob cov lus qhia ua tib zoo.
Thaum kawg, qhia koj tus kws kho mob txog koj li keeb kwm kev kho mob, tshwj xeeb tshaj yog cov kab mob myeloproliferative xws li kab mob raum, kab mob siab, thiab mob qog noj ntshav. Lwm yam tshuaj los yog kev kho mob yuav tsum tau hloov Ruxolitinib yog tias koj tsis haum rau nws.
Lub sij hawm xa tuaj: Plaub Hlis-25-2022