Paxlovid yog ib qho tshuaj tshawb nrhiav siv los kho tus mob me-rau-nruab nrab COVID-19 rau cov neeg laus thiab menyuam yaus [12 xyoo thiab laus dua qhov hnyav tsawg kawg 88 phaus (40 kg)] nrog cov txiaj ntsig zoo ntawm kev kuaj kab mob SARS-CoV-2 ncaj qha, thiab leej twg muaj kev pheej hmoo siab rau kev kis mus rau COVID-19 hnyav, suav nrog kev mus pw hauv tsev kho mob lossis tuag. Paxlovid yog kev tshawb nrhiav vim nws tseem tab tom kawm. Muaj cov ntaub ntawv txwv tsis pub hais txog kev nyab xeeb thiab kev ua tau zoo ntawm kev siv Paxlovid los kho cov neeg mob me-rau-nruab nrab COVID-19.
FDA tau tso cai rau kev siv thaum muaj xwm txheej ceev ntawm Paxlovid rau kev kho mob me me-rau-nruab nrab COVID-19 rau cov neeg laus thiab menyuam yaus [12 xyoo thiab laus dua qhov hnyav tsawg kawg nkaus 88 phaus (40 kg)] nrog rau kev kuaj pom tus kab mob zoo. ua rau COVID-19, thiab leej twg muaj kev pheej hmoo siab rau kev kis mus rau COVID-19 hnyav, suav nrog kev mus pw hauv tsev kho mob lossis tuag, raws li EUA.

Paxlovid tsis yog tshuaj FDA pom zoo hauv Tebchaws Meskas. Tham nrog koj tus kws kho mob txog koj cov kev xaiv lossis yog tias koj muaj lus nug. Nws yog koj xaiv coj Paxlovid.

Paxlovid muaj ob yam tshuaj: nirmatrelvir thiab ritonavir.

Nirmatrelvir [PF-07321332] yog SARS-CoV-2 lub ntsiab protease (Mpro) inhibitor (tseem hu ua SARS-CoV2 3CL protease inhibitor) uas ua haujlwm los ntawm inhibiting viral replication nyob rau theem pib ntawm tus kab mob los tiv thaiv kev loj hlob mus rau qhov mob hnyav heev. 19.

Ritonavir tau koom ua ke nrog nirmatrelvir los pab ua kom nws cov metabolism hauv qeeb kom nws nyob twj ywm hauv lub cev rau lub sijhawm ntev dua ntawm qhov siab dua los pab tiv thaiv tus kab mob.