2. Thalidomide hauv qog cachexia
Oncologic cachexia, ib qho kev mob qog noj ntshav siab tshaj plaws uas tshwm sim los ntawm anorexia, cov ntaub so ntswg depletion thiab poob phaus, yog ib qho kev sib tw loj hauv kev kho mob palliative ntawm kev mob qog noj ntshav.
Vim lub neej luv luv thiab tsis zoo ntawm lub neej ntawm cov neeg mob uas muaj mob qog noj ntshav, tus naj npawb ntawm cov kev kawm hauv kev tshawb fawb soj ntsuam me me, thiab cov kev tshawb fawb feem ntau tsuas yog ntsuas qhov ua tau zoo nyob ze thiab ze rau qhov tsis zoo ntawm thalidomide, yog li lub sijhawm ntev. Lub sij hawm ua tau zoo thiab lub sij hawm ntev tsis zoo ntawm thalidomide hauv kev kho mob ntawm oncologic cachexia tseem yuav tsum tau tshawb nrhiav hauv kev sim tshuaj nrog cov qauv loj.
3. Cov teebmeem tsis zoo cuam tshuam txog kev kho thalidomide
Cov kev phiv xws li kws khomob ntsig txog xeev siab thiab ntuav tuaj yeem cuam tshuam rau kev siv tshuaj khomob thiab txo cov neeg mob lub neej zoo.Txawm hais tias neurokinin 1 receptor antagonists tuaj yeem txhim kho cov kev cuam tshuam tsis zoo xws li xeev siab thiab ntuav, lawv daim ntawv thov kev kho mob thiab kev nce qib nyuaj vim yog cov neeg mob cov nyiaj txiag thiab lwm yam laj thawj.Yog li ntawd, kev tshawb nrhiav cov tshuaj muaj kev nyab xeeb, siv tau zoo thiab pheej yig los tiv thaiv thiab kho cov tshuaj kho mob nrog xeev siab thiab ntuav tau dhau los ua teeb meem kho mob ceev.
4. Cov lus xaus
Nrog rau kev txhim kho txuas ntxiv ntawm kev tshawb fawb hauv paus thiab kev kho mob, daim ntawv thov ntawmthalidomidenyob rau hauv kev kho mob ntawm cov qog nqaij hlav ntau tau nthuav dav, thiab nws cov kev kho mob thiab kev nyab xeeb tau raug lees paub thiab muab cov tswv yim kho tshiab rau cov neeg mob.Thalidomide tseem muaj txiaj ntsig zoo hauv kev kho mob qog nqaij hlav cachexia thiab kws khomob cuam tshuam nrog xeev siab thiab ntuav.Nyob rau hauv lub era ntawm precision kho tshuaj, nws yog ib qho tseem ceeb los soj ntsuam cov neeg tseem ceeb thiab cov qog subtypes uas zoo rauthalidomidekev kho mob thiab nrhiav biomarkers uas kwv yees nws cov kev ua tau zoo thiab qhov tsis zoo.